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Research Excellence

Researchers guide better use of medicines.

With the majority of older Australians taking five or more medications, a team from the Kolling Institute has developed a valuable tool to better understand adverse outcomes. The analytical resource has been developed by Professor Sarah Hilmer and Dr John Mach, after several years of research investigating the effects of using multiple medications. Previous studies have generally looked at the inte.....
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Category: Research Excellence

Gout cases increasing worldwide.

The prevalence of gout - a form of arthritis characterised by severe pain, redness and joint tenderness has increased across the world at an alarming rate. That’s according to Kolling Institute researcher Dr Emma Smith, who was the senior author of a research paper analysing the condition from 1990 to 2017. The paper, published in Arthritis & Rheumatology, found there were more than 41 million .....
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Category: Research Excellence

Research to help reduce smoking in pregnancy.

A large scale review has found the number of women smoking during pregnancy in NSW has halved, and yet there are still some concerning trends prompting calls for targeted campaigns. Researchers from the Kolling Institute and the University of Sydney, analysed smoking rates in all pregnancies in New South Wales over a 22 year period from 1994 to 2016. The Women and Babies Research team found the ove.....
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Category: Research Excellence

Which jobs put you at risk of developing a disabling knee condition?.

A global review has identified the jobs most likely to lead to knee osteoarthritis, prompting calls for greater measures to reduce the painful condition. More than 70 studies, involving nearly a million people were analysed as part of the biggest review of the knee condition. The international study brought together teams from the Universities of Sydney, Oxford and Southampton. Researchers found co.....
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Category: Research Excellence

New research challenges long-held views about high heels and joint pain .

New research has produced a surprising result, indicating high heel shoes may not be a problem for those with hip osteoarthritis. The condition is a very common joint disorder, contributing to tremendous pain for many older people and significant disability. Researchers from the Kolling Institute and the University of Sydney adopted an innovative approach, and evaluated the link between wearing sho.....
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Category: Research Excellence

Research may lead to early warning test for COVID-19.

For many people with COVID-19, the first sign they had the virus was a loss in their sense of smell. Now a team from the Kolling Institute and Royal North Shore Hospital will investigate the correlation between the virus and early symptoms. Study lead Associate Professor Rory Clifton-Bligh said a loss of smell has emerged as a common symptom of COVID-19 infection, but the current data is relying on.....
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Category: Research Excellence

Co-ordinated COVID-19 Research Response.

Kolling Institute researchers are a key part of a new Northern Sydney Local Health District COVID-19 Clinical Research Group. All major specialist disciplines are represented in the group, taking advantage of the breadth of knowledge across the health campus. Kolling researcher Associate Professor Clifton-Bligh said we formed the group because we saw a clear need to co-ordinate our clinical resear.....
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Category: Research Excellence

Important national COVID-19 study.

For many people with heart disease there’s an increased level of anxiety around the implications of COVID-19, but it’s hoped a new study led by Royal North Shore Hospital will guide future treatment and improve health outcomes. Head of cardiology Professor Ravinay Bhindi has launched the AUS-COVID study, which will involve more than 800 patients in over 20 hospitals across Australia. The Kolling I.....
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Category: Research Excellence

Multiple medications cause frailty, but this can be reversed .

A world-first study by a team from the Kolling Institute may inform the future use of multiple medications by older people, minimising adverse impacts including frailty. The longitudinal research is the first preclinical study to demonstrate that multiple medications can impair function in old age, and that stopping some can reduce harm. Research lead, Professor Sarah Hilmer said until now there’s.....
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Category: Research Excellence

Celebrating 100 years of research excellence.

2020 is an important year for the Kolling Institute as it marks the 100 year anniversary of the research organisation. As the longest-running medical research institute in New South Wales, the Kolling has a very rich history. Originally named the Institute of Pathological Research of NSW, the organisation was established in a cottage within the grounds of Royal North Shore Hospital in 1920. Bioche.....
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Category: Research Excellence